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. 2018 Dec 14;5(4):57. doi: 10.3390/jcdd5040057

Figure 1.

Figure 1

Schematic illustration of epigenetic regulation. Epigenetic regulation mainly comprises DNA methylation, histone modifications, chromatin remodeling complexes, and non-coding RNAs. CHD—CHD chromatin-remodeling complexes; K4, 9, 20, 27, 36, and R3—histone lysine (K) or arginine (R) methylation; K5, 8, 14, 18, and 23—histone lysine (K) acetylation; INO80—INO80 chromatin-remodeling complexes; ISWI—SWI-like ATP-dependent chromatin-remodeling complexes; miRNA—microRNA; Me—DNA methylation; pri-miRNA—primary miRNA; pre-miRNA—precursor miRNA; S10 and 28—histone phosphorylation; SWI/SNF—SWItch/sucrose nonfermentable complex; TF—transcription factor.