Table 1.
Characteristics of included patients and trial follow-up time by endpoint.
| # | N | Indication (Post-MI %) | Age (Mean Years, SD) | Sex (% male) | Follow-Up (Mean Months, SD) | |
|---|---|---|---|---|---|---|
| All Endpoints | 143 | 69,910 | 55 (37.2%) | 58.7 (6.4) | 83.1 | 36.5 (38.3) |
| Primary Endpoints | ||||||
| All-Cause Mortality | 118 | 44,462 | 50 (90.9%) | 58.9 (6.4) | 85.6 | 37.2 (35.9) |
| CV Mortality | 42 | 16,770 | 21 (38.2%) | 56.9 (6.5) | 92.9 | 47.9 (48.7) |
| Secondary Endpoints | ||||||
| Any MI | 52 | 16,690 | 28 (50.9%) | 55.6 (5.4) | 86.5 | 42.3 (43.7) |
| Fatal MI | 16 | 4261 | 9 (16.4%) | 53.7 (4.5) | 100.0 | 47.7 (51.8) |
| Non-Fatal MI | 31 | 11,919 | 18 (32.7%) | 54.5 (4.3) | 83.9 | 46.2 (47.3) |
| Any Revascularization | 49 | 16,947 | 25 (45.5%) | 56.8 (4.9) | 83.3 | 34.9 (38.9) |
| CABG | 33 | 7391 | 18 (32.7%) | 56.3 (4.9) | 84.4 | 33.0 (38.9) |
| PCI | 23 | 8859 | 10 (18.2%) | 56.8 (4.8) | 87.0 | 27.0 (16.0) |
| Any Hospitalization | 45 | 14,440 | 16 (29.1%) | 59.0 (5.8) | 82.6 | 31.5 (33.5) |
| CV Hospitalization | 24 | 7925 | 10 (18.2%) | 57.6 (4.1) | 88.0 | 28.5 (30.1) |
# = Number of trials reporting endpoint. N = number of patients randomized. SD = standard deviation. CV = cardiovascular. MI = myocardial infarction. CABG = coronary artery bypass surgery. PCI = percutaneous coronary intervention.