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. 2018 Jun;18(2):295–303. doi: 10.4314/ahs.v18i2.14

Table 2.

Sensitivities, Specificities, PPVs, NPVs and Likelihood Ratios for the various auto antibodies

Sensitivity
% (95CI)
Specificity
% (95CI)
PPV
% (95CI)
NPV
% (95CI)
Likelihood
Ratio
cRF 86.7 (76.8 –93.4) 90.7 (82.5– 95.9) 89.0 (79.5– 95.2) 88.6 (80.1– 94.4) 9.32
ACPA 86.7 (76.8 –93.4) 86.0(77.3– 92.3) 83.3 (73.2 – 90.8) 88.9 (80.5– 94.5) 6.19
RF-IgA 50.0 (33.8–66.2) 58.2(32.9– 81.6) 74.1 (53.7– 88.9) 33.3 (17.2 – 52.8) 1.20
ACPA-IgA 30.7 (20.5 – 42.4) 95.0 (75.1 – 99.9) 95.8 (78.9 – 99.9) 26.8 (16.9 – 38.6) 1.76

Highest results achieved are in BOLD