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. 2018 Nov 26;7(12):481. doi: 10.3390/jcm7120481

Table 3.

Risk factors for pre-frail and frail status by odds ratio in logistic regression analysis

Pre-Frailty and Frailty (Versus Robust)
Variable Univariate Model Multivariate Model *
Odds Ratio 95% CI p Value Odds Ratio 95% CI p Value
Lower Limit Upper Limit Lower Limit Upper Limit
Age (years) 1.03 1.00 1.06 0.07 1.02 0.98 1.05 0.33
Sex
Female 1.00 1.00
Male 0.88 0.63 1.21 0.42 1.06 0.74 1.52 0.76
BMI (kg/m2) 1.05 0.99 1.11 0.09 1.04 0.98 1.11 0.18
Education level
Illiterate 2.84 1.42 5.71 <0.01 1.66 0.65 4.24 0.29
Elementary school 2.34 1.23 4.45 0.01 1.46 0.63 3.41 0.38
Junior/senior high school 1.56 0.78 3.10 0.21 0.95 0.42 2.18 0.91
College or above 1.00 1.00
Health literacy
Inadequate 3.39 1.93 5.94 <0.01 1.71 0.82 3.56 0.15
Problematic 1.65 0.99 2.76 0.06 1.11 0.58 2.14 0.74
Sufficient 3.06 1.80 5.21 <0.01 2.51 1.32 4.77 0.01
Excellent 1.00 1.00
Annual income
No income 1.92 0.97 3.82 0.06 1.52 0.72 3.22 0.28
≤8000 USD 1.14 0.79 1.64 0.48 0.99 0.65 1.51 0.96
>8000 USD 1.00 1.00
Comorbidities
(No. of diseases)
0–2 1.00 1.00
≥3 1.91 1.16 3.14 0.01 1.35 0.78 2.32 0.28
Polypharmacy
(No. of medications)
<5 1.00 1.00
≥5 1.40 0.99 1.99 0.06 1.02 0.69 1.52 0.92
GDS-5 score
<2 1.00 1.00
≥2 1.92 1.26 2.93 <0.01 1.58 0.99 2.52 0.053
Physical activity (IPAQ)
Insufficiently active 1.47 1.06 2.03 0.02 1.55 1.07 2.23 0.02
Sufficiently/highly active 1.00 1.00
Protein intake (g/kg/day)
<0.8 1.15 0.52 2.55 0.72 1.06 0.45 2.53 0.89
0.8–1 0.71 0.30 1.68 0.44 0.70 0.28 1.73 0.44
≥1 1.00 1.00

GDS-5, Geriatric depression scale-5; IPAQ, International Physical Activity Questionnaires. * Adjusted R squared = 0.115.