Effects of Lf on MAPK signaling pathways in mice. (A) Changes in expression levels of p-ERK1/2, ERK1/2, p-CREB, CREB, p-JNK1/2, JNK1/2, p-p38 and p38 in three groups of mice by Western blots. Quantitative analysis of the proteins shown in B-F. Values are represented as the means ± SD (n = 10). *p < 0.05, **p < 0.01 compared with the Control group; #p < 0.05, ##p < 0.01 compared with the MPTP group.