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. 2018 Dec 27;9:25. doi: 10.1186/s13326-018-0192-y

Table 2.

Summary of articles discussing glutamate and epilepsy

Study Subjects Method Result/Conclusion
Juhász et al. [50] Epileptic children with Sturge-Weber syndrome Proton magnetic resonance spectroscopic brain imaging Increased glutamate concentrations observed
Cavus et al. [52] Epileptic and nonepileptic cortical sites in patients with refractory epilepsy High-performance liquid chromatography based on microdialysis probes Elevated extracellular glutamate observed at epileptogenic sites
Perez et al. [53] Tissue extracted from brains of male Sprague Dawley rats infused with methionine sulfoximine Glutamate levels measured with immunogold electron microscopy Glutamine synthetase deficiency leads to increased extracellular glutamate