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. 2018 Dec 27;37:324. doi: 10.1186/s13046-018-0965-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Exosomal miRNA-21 activates HSCs via PTEN/PDK1/AKT signaling axis. a, b Immunoblotting assays of indicated proteins in HSCs treated with control or exosomes from different tumor cells. c-e Western blotting assays of indicated proteins in HSCs with indicated treatments. Each experiment was performed in triplicate, and data are presented as mean ± s.d. Student’s t-test was used to analyze the data (*p < 0.05; **p < 0.01; ***p < 0.001)