Table 3.
Cox Regression model with caffeine (any vs. none)
| Risk Factor | Estimate | P-value | Hazard Ratio (HR) (95% CI for HR) |
|---|---|---|---|
| Age | 0.079 | < 0.001 | 1.083 (1.034, 1.133) |
| Sex (Male) | 0.175 | 0.583 | 1.191 (0.638, 2.224) |
| Race (White) | − 1.030 | 0.069 | 0.357 (0.117, 1.085) |
| BMI | 0.047 | 0.131 | 1.048 (0.986, 1.114) |
| Smoke (Yes) | 1.042 | 0.017 | 2.836 (1.204, 6.683) |
| Hypertension (Yes) | 1.528 | 0.003 | 4.611 (1.711, 12.426) |
| Gene typea | |||
| PKD1 + no truncation | 0.375 | 0.273 | 1.455 (0.745, 2.841) |
| PKD2 + NMD | −1.636 | 0.010 | 0.195 (0.057, 0.672) |
| Caffeine (Any) | −0.587 | 0.096 | 0.556 (0.279, 1.110) |
aReference group: PKD1 + truncation. NMD refers to no mutation detected in the genetic analysis