Table 3.
Top 4 SNPs associated to CES total editing rate define a locus on chromosome 7
| SNP | Chr | Position | A1 | Beta | p value (cell corrected p) | r 2 | Gene (distance) |
|---|---|---|---|---|---|---|---|
| rs856554* | 7 | 46,760,129 | G | 0.00377 | 3.90 × 10− 08 (3.29 × 10− 05) |
– | LOC730338](23.4 kb) |
| rs856589 | 7 | 46,734,307 | A | 0.00345 | 8.37 × 10 − 08 (4.38 × 10− 05) |
0.73 | [LOC730338] |
| rs6463347 | 7 | 46,780,614 | C | 0.00350 | 1.34 × 10− 07 (8.09 × 10− 05) |
0.76 | LOC730338](43.9 kb) |
| rs856565 | 7 | 46,721,854 | A | 0.00347 | 2.53 × 10−07 (2.58 × 10−04) |
0.88 | [LOC730338 (5.6 kb) |
For each SNP, the table reports distance from LOC730338 gene. Gene name within square brackets indicate SNPs located within the gene, while single bracket indicates 3′ and 5' distance. Index SNP is marked with *. r2 with the index SNP is reported for other SNPs in the locus. Genomic coordinates refer to hg19 genome assembly