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. 2018 Dec 27;18:201. doi: 10.1186/s12862-018-1315-x

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Original OAS genes are not involved in the OAS/RNaseL antiviral pathway. Genes related to the OAS/RNaseL pathway are displayed. IFN, IFNR, STAT1, STAT2, and RNaseL (colored in gray) have not been found in lower Metazoa. OAS genes and JAK-like genes are widely distributed in lower Metazoa