Table 1.

Distribution of OAS related genes in lower Metazoa

Latin name	Common name	OAS	Identity to hOAS1	IFN	STAT 1/2	JAK	IFNR	RNaseL	TOP I	Identity to hTOPI
Geodia cydonium	Demosponge	++	26%	–	–	–	–	–	–
Tedania ignis	Fire sponge	++	28%	–	–	–	–	–	–
Amphimedon queenslandica	Demosponge	++	28%	–	–	+	–	–	++	62%
lubomirskia baicalensis	Demosponge	++	23%	–	–	–	–	–	–
Acropora digitifera	Acropora coral	++	31%	–	–	+	–	–	++	70%
Nematostella vectensis	Startlet sea anemone	++	30%	–	–	+	–	–	++	71%
Orbicella faveolata	Mountaius star coral	++	33%	–	–	+	–	–	++	68%
Orchesella cincta	Springtails	++	25%	–	–	+	–	–	++	67%
Crassostrea gigas	Pacific oyster	++	30%	–	–	+	–	–	++	72%
Lottia gigantea	Owl limpet	++	28%	–	–	–	–	–	++	72%
Lingula anatina	Lamp shell	++	31%	–	–	+	–	–	++	64%
Saccoglossus kowalevskii	Acorn worm	++	28%	–	–	+	–	–	++	73%

++: Nearly complete sequences; +: Fragments; −: No hits found

hOAS1 human OAS1 protein, hTOPI human TOPI protein