Table 3.
Binary logistic regression analysis with odds ratios for markers of morbidity
| Lengths of stay ICU ≥ 3 days | Mechanical ventilation ≥ 8.5 h | Fluid balance ≥ 2.8 l | Use of inotropic drugs (Y/N) | Increase in creatinine ≥ 30 μmol/l | |
|---|---|---|---|---|---|
| Model 1: RVEF as a continuous variable | |||||
| RVEF (%) | 0.934 [0.908–0.961] p < 0.001* | 0.969 [0.942–0.998] p = 0.033* | 0.974 [0.947–1.002] p = 0.065 | 0.944 [0.917–0.971] p < 0.001* | 0.962 [0.934–0.991] p = 0.011* |
| Age (years) | 0.984 [0.969–0.999] p = 0.038* | 0.988 [0.972–1.004] p = 0.143 | 0.995 [0.979–1.011] p = 0.538 | 0.982 [0.968–0.997] p = 0.018* | 1.000 [0.982–1.016] p = 0.907 |
| Bodyweight (kg) | 1.001 [0.991–1.010] p = 0.914 | 1.000 [0.989–1.010] p = 0.942 | 0.998 [0.988–1.009] p = 0.760 | 0.996 [0.986–1.005] p = 0.393 | 1.019 [1.009–1.029] p = < 0.001* |
| COPD | 1.192 [0.833–1.706] p = 0.336 | 1.136 [0.777–1.661] p = 0.510 | 1.120 [0.774–1.620] p = 0.548 | 1.110 [0.764–1.613] p = 0.584 | 0.824 [0.557–1.219] p = 0.332 |
| Unstable angina | 4.599 [2.309–9.163] p < 0.001* | 4.671 [2.433–8.969] p < 0.001* | 2.302 [1.237–4.284] p = 0.008* | 1.538 [0.665–3.552] p = 0.314 | 1.203 [0.615–2355] p = 0.589 |
| Poor LVEF† | 1.385 [0.950–2.020] p = 0.091 | 1.044 [0.737–1.479] p = 0.807 | 0.806 [0.536–1.212] p = 0.300 | 11.579 [6.393–20.973] p < 0.001* | 1.453 [0.986–2.139] p = 0.059 |
| Pulmonary hypertension | 1.321 [0.662–2.635] p = 0.430 | 1.187 [0.574–2.453] p = 0.644 | 1.067 [0.516–2.206] p = 0.861 | 2.284 [0.931–5.601] p = 0.071 | 2.179 [1.113–4.268] p = 0.023* |
| APACHE IV score | 1.061 [1.049–1.073] p < 0.001* | 1.057 [1.045–1.068] p < 0.001* | 1.044 [1.034–1.055] p < 0.001* | 1.038 [1.027–1.050] p < 0.001* | 1.050 [1.039–1.061] p = < 0.001* |
| Model 2: RVEF as a categorical variable with RVEF > 30% as reference group | |||||
| RVEF 20–30% | 2.050 [1.258–3.340] p = 0.004* | 1.301 [0.794–2.131] p = 0.297 | 1.422 [0.878–2.302] p = 0.152 | 1.559 [1.050–2.316] p = 0.028* | 1.190 [0.741–1.910] p = 0.472 |
| RVEF < 20% | 3.250 [1879–5.621] p < 0.001* | 1.896 [1.093–3.288] p = 0.023* | 1.732 [1.007–2.977] p = 0,047* | 2.259 [1.359–3.754] p = 0.002* | 1.633 [0.949–2.812] p = 0.077 |
* Indicates a significant difference across groups. † Left ventricular ejection fraction < 30%
Abbreviations: CI, confidence interval; RVEF, right ventricular ejection fraction; ICU, intensive care unit; COPD, chronic obstructive pulmonary disease; LVEF, left ventricular ejection fraction; APACHE, Acute Physiology and Chronic Health Evaluation