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. 2018 Dec 27;18:218. doi: 10.1186/s12935-018-0712-y

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — PD-1 expression between cancer samples and normal samples of 22 types of cancer. The expression of PD-1 in LIHC, PRAD, BRCA, KIRP, CHOL, HNSC, UCEC, KIRC, LUSC, and LUAD was upregulated, while it was downregulated in KICH and THCA (P < 0.05). Because of small size of normal tissue samples, eleven cancer types were excluded for expression profile analysis between tumor tissue samples and normal tissue samples. *P < 0.05, **P < 0.01, ***P < 0.001