Figure 4.

Expression of migration and apoptosis-associated proteins in lung cancer cell lines following treatment with gefitinib with or without Rg3. Protein expression levels of caspase-3, Bax, Bcl-2, E-cadherin, SLUG, SNAIL and GAPDH were determined using western blot analysis in (A) A549 and (B) H1299 cells treated with gefitinib (10 µM) with or without Rg3 (12.5 µg/ml) for 24 h. Rg3, ginsenoside Rg3; H1299 and A549, non-small cell lung cancer cell lines. Bax, Bcl-2-associated X; Bcl-2, B-cell lymphoma 2; SLUG, snail family transcriptional repressor 2; SNAIL, snail family transcriptional repressor 1.