Table 1.
Demographic characteristics of PD patients without and with LID development at 48 months follow-up.
| PD patients without LID at 48 months (n = 254) | PD patients with LID at 48 months (n = 36) | p-value | |
|---|---|---|---|
| Age at PD onset (years) | 61.0 ± 9.8 | 61.0 ± 9.4 | 0.97 |
| EOPD (n, %) | 31, 12.2 % | 4, 11.1 % | 0.85 |
| Gender (Male: Female) | 174: 80 | 21: 15 | 0.22 |
| Weight (Kg) | 82.1 ± 17.3 | 79.4 ± 17.1 | 0.39 |
| Duration of Parkinson's disease symptoms until study enroll | 23.6 ± 22.2 | 23.8 ± 18.9 | 0.94 |
| Hoehn and Yahr staging at baseline | 1.5 ± 0.5 | 1.7 ± 1.5 | 0.06 |
| MDS-UPDRS Part II score at baseline | 6.3 ± 4.0 | 9.5 ± 4.3 | < 0.001 |
| MDS-UPDRS Part III score at baseline | 19.9 ± 8.4 | 23.7 ± 7.8 | < 0.01 |
| Use of dopamine agonist, % | 63.3 | 47.2 | 0.06 |
| Average LEDD at 48 months (g) | 1192 ± 1168 | 1332 ± 863 | 0.07 |
The values presented are the numbers or mean ± standard deviation.