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. 2018 Nov 23;17(1):857–862. doi: 10.3892/etm.2018.7005

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Figure 1. — Expression of ZEB1-AS1 in melanoma and its effect on overall survival. (A) Reverse transcription-quanitative polymerase chain reaction analysis of various melanoma cell lines and HEMa cells indicated that ZEB1-AS1 is overexpressed in melanoma cells. (B) Compared to normal tissue (n=46), ZEB1-AS1 is highly expressed in melanoma tissue (n=46). (C) Kaplan-Meier analysis of overall survival of melanoma patients stratified based on ZEB1-AS1 expression (high or low). Higher levels of ZEB1-AS1 expression predict poor overall survival. *P<0.05, **P<0.01 vs. normal/HEMa. ZEB1-AS1, zinc finger E-box binding homeobox 1 antisense RNA 1; HEMa, human primary normal epidermal melanocytes.