Table I.
Expression of CLDN12 and clinicopathological characteristics of the patients with lung squamous cell carcinoma.
| Item | n | CLDN12 (+) | CLDN12 (−) | P-value |
|---|---|---|---|---|
| Tumor tissue | 50 | 32 | 18 | <0.001 |
| Normal mucosa | 20 | 5 | 15 | |
| Age (years) | 0.794 | |||
| ≤60 | 22 | 14 | 8 | |
| >60 | 28 | 18 | 10 | |
| Smoker | 0.372 | |||
| Yes | 30 | 17 | 13 | |
| No | 20 | 15 | 5 | |
| E-Cadherin | 0.001 | |||
| + | 29 | 13 | 16 | |
| − | 21 | 19 | 2 | |
| Histological grade | 0.812 | |||
| Well and moderately differentiated | 24 | 15 | 9 | |
| Poorly differentiated | 26 | 17 | 9 | |
| Lymph node metastasis | 0.001 | |||
| + | 27 | 21 | 6 | |
| − | 23 | 11 | 12 | |
| Grade | 0.736 | |||
| I–II | 35 | 22 | 13 | |
| III–IV | 15 | 10 | 5 |
P-values were determined with the χ2 test. CLDN12, claudin-12.