Table I.
Energy metabolism-related enzymes activities and ATP level.
| Enzyme activity | Wogonin (SGC-7901) | Control (SGC-7901) | Wogonin (A549) | Control (A549) |
|---|---|---|---|---|
| HK (U/g prot) | 49.80±5.41 | 56.56±6.49 | 48.61±0.41 | 47.09±6.49 |
| PK (U/g prot) | 2,156.56±135.61 | 1,975.76±94.71 | 2,507.98±191.61 | 3,206.05±469.47 |
| LDH (U/g prot) | 216.22±8.95b | 3301.54±263.39 | 8406.95±506.35b | 12,805.51±803.25 |
| SDH (U/mg prot) | 239.07±6.83a | 382.46±15.89 | 525.27±46.54 | 511.90±36.24 |
| ATP (µmol/g prot) | 3,090.50±456.35a | 4,595.84±563.52 | 1,219.45±314.87a | 2,428.03±203.99 |
Values are expressed as the mean ± standard deviation, n=4.
a
P<0.05
b
P<0.01 vs. the control. HK, hexokinase; PK, pyruvate kinase; LDH, lactate dehydrogenase; SDH, succinate dehydrogenase.