Table II.
Comparison of inflammatory factors, osteoporosis indicators and vitamin D of patients among different groups.
| Index | CKD I–II stage | CKD III–IV stage | CKD V stage |
|---|---|---|---|
| IL-6 (pg/ml) | 99.2±9.3 | 125.3±10.3a | 189.2±10.7a,b |
| CRP (µg/ml) | 2.9±0.2 | 6.4±0.6a | 20.3±2.0a,b |
| TNF-α (ng/ml) | 1.22±0.12 | 1.79±0.18a | 2.23±0.23a,b |
| Serum calcium (mmol/l) | 2.2±0.2 | 2.0±0.2a | 1.5±0.2a,b |
| Serum phosphate (mmol/l) | 1.3±0.1 | 1.6±0.1a | 2.0±0.2a,b |
| BMD | 0.923±0.086 | 0.823±0.098a | 0.723±0.067a,b |
| 25(OH)D (ng/ml) | 20.5±2.3 | 14.9±1.7a | 6.3±0.8a,b |
| Serum sodium (mmol/l) | 134.43±11.56 | 146.67±14.09a | 152.09±15.21a,b |
| Serum potassium (mmol/l) | 3.86±0.45 | 4.32±0.39a | 4.78±0.49a,b |
| BUN (mml/l) | 13.67±1.65 | 14.87±1.98a | 16.02±1.99a,b |
a
P<0.05, compared with CKD I–II stage group
b
P<0.05, compared with CKD III–IV stage group. CKD, chronic kidney disease; IL-6, interleukin-6; CRP, C-reactive protein; TNF-α, tumor necrosis factor-α; BMD, bone mineral density; BUN, blood urea nitrogen.