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. 2018 Nov 6;17(1):17–26. doi: 10.3892/etm.2018.6932

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — HMGB1 immunohistochemical staining of renal tissues. (A) Control. (B) CH group. (C) IH group. (D) IHH group. The expression of HMGB1 was identified primarily in the nucleus of the renal tubular epithelial cells, as demonstrated in (A). The expression and translocation of HMGB1 was increased in the (B) CH group, (C) IH group and (D) IHH group compared with the control. IHH, intermittent hypoxia with hypercapnia; IH, intermittent hypoxia; CH, continuous hypoxia; HMGB1, high mobility group box 1 protein.