Figure 3.

Scanning electron microscopy images of the constructs. (A) PCL frameworks exhibited macroporous (~1,000 µm) architectures with complete interconnectivity. In the COL-modified PCL scaffold (PCL/COL), microporous (126.2±18.42 µm) COL networks homogeneously occupied the voids of the framework and covered the trabecula of the PCL scaffold. PLGA microspheres were evenly distributed in the COL of the PCL/COL/SIM-PLGA scaffold, with minor only effects on the pore structure and porosity. Summary of (B) pore structure and (C) porosity. *P<0.05, as indicated. PLGA, poly (lactic-co-glycolic acid); SIM, simvastatin; COL, collagen; PCL, poly(ε-caprolactone).