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. 2018 Nov 9;17(1):79–90. doi: 10.3892/etm.2018.6947

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — In vitro cellular evaluation of the PCL/COL/SIM-PLGA composite constructs. (A) Cell seeding efficiency assay. (B) Cytotoxicity evaluation of the extracted liquid of the scaffolds. (C) Level of cell proliferation in the scaffolds. The PCL/COL/SIM-PLGA scaffold possessed the greatest biocompatibility and exhibited more favorable biological properties, achieving better cellular adhesion and proliferation capacities. *P<0.05, as indicated. PLGA, poly(lactic-co-glycolic acid); SIM, simvastatin; COL, collagen; PCL, poly(ε-caprolactone), DBM, decalcified bone matrix; OD, optical density.