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. 2018 Nov 9;17(1):79–90. doi: 10.3892/etm.2018.6947

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 6. — Gene expression analyses of (A) ALP, (B) COL 1, (C) BSP, (D) OPN, (E) RUNX2 and (F) OCN in the different groups after 7 and 14 days of culture. The results are presented as relative ratios to the PCL group at day 7. The expression of osteogenic genes was greatly enhanced by the PCL/COL/SIM-PLGA scaffold. *P<0.05, as indicated. PLGA, poly(lactic-co-glycolic acid); SIM, simvastatin; COL, collagen; PCL, poly(ε-caprolactone); ALP, alkaline phosphatase; COL 1, collagen type 1; BSP, bone sialoprotein; RUNX2, runt-related transcription factor 2; OPN, osteopontin; OCN, osteocalcin.