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. 2018 Nov 9;17(1):79–90. doi: 10.3892/etm.2018.6947

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — Analysis of bone regeneration of the femur defect with the implanted scaffolds using X-ray and micro-CT. (A) Plain X-ray images of the femur defects at 4 and 12 weeks after transplantation with PCL, PCL/COL or PCL/COL/SIM-PLGA. Micro-CT scan of the femur bone defect at 3 months after surgery. (B) Bone volume. The rats in the PCL/COL/SIM-PLGA group exhibited improved bone repair when compared with the other groups. *P<0.05, as indicated. PLGA, poly(lactic-co-glycolic acid); SIM, simvastatin; COL, collagen; PCL, poly(ε-caprolactone); CT, computed tomography.