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Expression of OCN in the defect area. (A) Representative images of immunohistochemical staining of OCN. (B) Percentage of positively stained cells per field of view was calculated. The PCL/COL/SIM-PLGA group exhibited the greatest levels of OCN staining. *P<0.05, as indicated. PLGA, poly(lactic-co-glycolic acid); SIM, simvastatin; COL, collagen; PCL, poly(ε-caprolactone); OCN, osteocalcin.
