Effects of swimming intervention on (A) IRS-1 phosphorylation and (B) GLUT4 expression, detected by western blot analysis. Swimming intervention promoted IRS-1 phosphorylation and GLUT4 expression in patients with metabolic syndrome. *P<0.05. IRS-1, insulin receptor substrate-1; GLUT-4, glucose transporter type 4; C, healthy controls; group A, metabolic syndrome with no swimming intervention; group E, swimming intervention for 60 min per session.