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. 2018 Dec 20;9:1469. doi: 10.3389/fphar.2018.01469

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Copyright © 2018 Mao, Yi, Wang, Huang and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of cos on the expression of p65 protein. (I) Western blot analysis of cytosol and nucleus p65 proteins. (II) Immunohistochemistry analysis of NF-κB (p65). (II-A) Control; (II-B) LPS/D-GalN (LPS 50 μg/kg; D-GalN: 400 mg/kg); (II-C) LPS/D-GalN + L-cos (II-B + cos 20 mg/kg); (II-D) LPS/D-GalN + H-cos (II-B + cos 40 mg/kg); (II-E) LPS/D-GalN + sily (II-B + sily 20 mg/kg). The density values of the western blot were normalized for β-actin and Lamin B. ^∗∗∗P < 0.01 vs. control group, ^###P < 0.01 vs. LPS/D-GalN group.