Table 1.
Total cohort (n=241) |
No ARDS (n=66) |
ARDS (n=15) |
P value | |
Demographics | ||||
Age (years) | 45 (27–59) | 37 (23–56) | 38 (25–58) | 0.67 |
Gender (% male) | 178 (74) | 40 (61) | 15 (100) | 0.003* |
MOI (% blunt) | 232 (96) | 62 (94) | 15 (100) | 0.33 |
ISS | 29 (22–36) | 25 (19–29) | 30 (26–41) | 0.01* |
AIS head | 3 (1–4) | 3 (0–4) | 2 (0–4) | 0.13 |
AIS face | 0 (0–2) | 0 (0–1) | 0 (0–2) | 0.70 |
AIS chest | 3 (2–4) | 3 (1–3) | 4 (3–4) | 0.04* |
AIS abdomen | 1 (0–3) | 1 (0–2) | 2 (0–3) | 0.57 |
AIS extremities/pelvis | 2 (1–3) | 2 (0–3) | 3 (0–3) | 0.20 |
AIS external | 0 (0–1) | 0 (0–1) | 1 (0–1) | 0.62 |
Pelvic fracture | 75 (31) | 21 (32) | 4 (27) | 0.70 |
Urgent laparotomy | 61 (25) | 16 (24) | 6 (40) | 0.22 |
Resuscitation | ||||
Crystalloids (L) | ||||
<8 hours | 4.7 (2.6–6.5) | 4.5 (1.5–5.9) | 4.9 (2.0–7.0) | 0.33 |
<24 hours | 7.6 (5.3–10.4) | 6.8 (3.3–9.5) | 8.7 (5.9–12.8) | 0.03* |
PRBC (U) | ||||
<8 hours | 1 (0–4) | 0 (0–3) | 3 (0–7) | 0.18 |
<24 hours | 1 (1–6) | 1 (0–3) | 3 (0–9) | 0.24 |
FFP (U) | ||||
<8 hours | 0 (0–4) | 0 (0–2) | 2 (0–4) | 0.05 |
<24 hours | 0 (0–5) | 0 (0–2) | 3 (0–4) | 0.04* |
PLT (U)† | ||||
<8 hours | 0 (0–0) | 0 (0–0) | 0 (0–1) | 0.01* |
<24 hours | 0 (0–1) | 0 (0–0) | 0 (0–2) | 0.02* |
Outcome | ||||
Ventilator days | 7 (3–12) | 2 (1–3) | 11 (6–17) | <0.001* |
ICU-LOS (days) | 8 (4–14) | 3 (2–4) | 12 (8–19) | <0.001* |
H-LOS (days) | 23 (14–34) | 15 (10–23) | 33 (14–43) | 0.004* |
MODS | 76 (32) | 2 (3) | 6 (40) | <0.001* |
Mortality | 31 (13) | 2 (3) | 3 (20) | 0.01* |
Data are expressed as median (IQR) or absolute number (%).
*Statistically significant.
†1 unit of platelets contains five donors.
AIS, Abbreviated Injury Scale; ARDS, Acute Respiratory Dysfunction Syndrome; FFP, fresh frozen plasma; H-LOS, hospital length of stay;ICU-LOS, intensive care unit length of stay; ISS, Injury Severity Score; MODS, Multiple Organ Dysfunction Syndrome; MOI, mechanism of injury; PLT, platelet; PRBC, packed red blood cells.