Tab.3.
KEGG pathway analysis for differentially expressed genes in the liver of LepΔI14/ΔI14 and WT rats.
| KEGG pathways | P-value | Gene |
|---|---|---|
| MAPK signaling pathway | 1.6E-08 | Pla2g4a;Fgf21;Mapk11;Cdc25b;Myc;Hspa1b;Jun;Pla2g12a;Dusp1;Cacng4;Rela;Map2k4;Fgfr3;Mapk4;Map3k10 |
| Regulation of actin cytoskeleton | 2.71E-06 | Fgf21;Myh10;Pip5k1b;Pip5k1a;Arhgef12;Gsn;Pip5k1c;Mylk;Fgfr3;Fn1;Pak4 |
| Jak-STAT signaling pathway | 2.78E-04 | Il3ra;Myc;Cish;Socs7;Il13ra2;Spred1;Lifr |
| Adipocytokine signaling pathway | 2.95E-04 | Irs3;Slc2a1;Ppara;Irs2;Rela |
| Neuroactive ligand-receptor interaction | 4.17E-04 | Grin1;Adora1;Gpr77;P2ry6;Prlhr;Nmu;Trpv1;Ntsr1;Taar7a;Gabrg3 |
| PPAR signaling pathway | 4.44E-04 | Me1;Fabp4;Fads2;Ppara;Ppard |
| Wnt signaling pathway | 3.7342E-02 | Myc;Jun;Ppard;Nkd2 |
| Calcium signaling pathway | 5.82E-05 | Grin1;Atp2b2;Tnnc2;Plce1;Plcd3;Mylk;Ntsr1;Atp2b4;Itpr1 |