Table 4.
MiRNAs, genes, and TFs with the highest (top 5%) betweenness centrality (BC) in the DmiR_TF_Net in HCM
| miRNAs | BC | Genes | BC | TFs | BC |
|---|---|---|---|---|---|
| hsa‐miR‐182‐5p | 0.1667 | PDK4 | 0.1667 | STAT3∆ | 0.2252 |
| hsa‐miR‐155‐5p∆ | 0.1311 | CCND2 | 0.1144 | HIF1A#∆ | 0.1605 |
| hsa‐miR‐124‐3p∆ | 0.1205 | FASN#∆ | 0.1053 | FOS#∆ | 0.1508 |
| hsa‐miR‐34a‐5p# | 0.1161 | SERPINE1∆ | 0.0916 | ||
| hsa‐miR‐17‐5p#∆ | 0.0891 | SCD | 0.0369 | ||
| hsa‐miR‐181a‐5p | 0.0496 |
miRNAs and TFs with “∆” denote the miRNAs, genes, and TFs are within top 5% dysregulated FFLs, and those with “#” indicate the known miRNAs, genes, and TFs associated with HCM.