Figure 3.

Direct binding between miR‐129‐2‐3p and the 3′UTR of gene SYK. (A) in silico prediction of miR‐129‐2‐3p and SYK mRNA interactions showed the potential targeting sites on the 3′UTR of SYK gene. The HEK293T cells (B) and HUVECs (C) were cotransfected with luciferase constructs and mimic control/miR‐129‐2‐3p respectively. After transfection for 24 hours, the relative luciferase activity was analysed by Dual‐luciferase reporter system. Data were represented as mean ± SD from three independent experiments. ***P < 0.001 compared with the control groups analysed by one‐way ANOVA