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. 2018 Oct 24;23(1):453–463. doi: 10.1111/jcmm.13948

Figure 7.

Figure 7

Diagram of the possible mechanisms of TDD‐induced effects in LPS‐stimulated EA.hy926 Cells. TDD as a HMBOX1 activator to suppress LPS‐stimulated inflammation and ROS production, subsequent inhibition of redox‐sensitive NF‐κB and MAPK activation