Figure 1.

Schematic illustration of experimental groups. A group of mice was given a single IP injection of cisplatin (15 mg/kg). Mice in the control groups were treated (IP) with Captisol (vehicle) or DAPT (15 mg/kg) alone. Another group received DAPT 1 h before cisplatin administration, followed by daily DAPT injection for 4 days. The injection volume was kept at 10 μL/g body weight