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Schematic diagram of the functions of lncRNA‐MALAT1 during hypoxia induced pro‐survival autophagy in human endometrial stromal cells. In normoxia condition, HIF‐1α protein is rapidly degraded by the ubiquitin‐proteasome system. In hypoxia condition, HIF‐1α is stabilized and translocated into the nucleus by importin α/β and dimerizes with HIF‐1β. The HIF heterodimer affects transcription of downstream target lncRNA‐MALAT1, which promotes the induction of pro‐survival autophagy
