Table 2.
Polymorphic status of microsatellite markers used and the observed genetic changes of DVL1, DVL2 and DVL3 genes
Patient no | Grade | DVL1 | DVL2 | DVL3 |
---|---|---|---|---|
D1S468 & D1S243 | D17S960 | D3S1262 | ||
1 | I | HETERO | HOMO | HETERO |
2 | I | HETERO | HOMO | HETERO |
3 | I | HETERO | HETERO | HETERO |
4 | I | HETERO | HETERO | HETERO |
5 | I | HETERO | HETERO | HOMO |
6 | I | MSI | LOH | MSI |
7 | I | HETERO | HOMO | MSI |
8 | I | MSI | MSI | MSI |
9 | I | HETERO | HOMO | HETERO |
10 | I | MSI | HOMO | HETERO |
11 | I | MSI | HETERO | HETERO |
12 | I | HETERO | HOMO | HETERO |
13 | I | HETERO | HETERO | HETERO |
14 | I | HETERO | HETERO | HETERO |
15 | II | HETERO | HETERO | HETERO |
16 | II | HETERO | LOH | HETERO |
17 | II | MSIa | LOH | MSI |
18 | II | MSI | HETERO | HETERO |
19 | II | MSI | MSI | HETERO |
20 | II | MSIa | HOMO | HETERO |
21 | II | HETERO | HOMO | HETERO |
22 | II | HETERO | HOMO | HETERO |
23 | II | MSI | HETERO | HETERO |
24 | II | HETERO | HETERO | HOMO |
25 | II | MSI | MSI | MSI |
26 | II | MSI | LOH | HOMO |
27 | II | MSI | HETERO | HETERO |
28 | III | HETERO | HOMO | HETERO |
29 | III | MSI | HETERO | LOH |
30 | III | LOH | LOH | MSI |
31 | III | MSI | HOMO | HETERO |
32 | III | HETERO | HETERO | MSI |
33 | III | HETERO | HOMO | HETERO |
34 | III | MSI | HOMO | MSI |
35 | III | MSI&LOH | HETERO | HETERO |
36 | III | MSI | HETERO | HETERO |
37 | III | MSI | LOH | HETERO |
38 | III | HETERO | HOMO | HETERO |
39 | IV | HETERO | HOMO | LOH |
40 | IV | MSI&LOH | HETERO | HETERO |
41 | IV | HETERO | HETERO | MSI |
42 | IV | MSI | HOMO | HETERO |
43 | IV | HETERO | HOMO | HETERO |
44 | IV | MSI | HOMO | HOMO |
45 | IV | LOH | HETERO | HETERO |
46 | IV | MSI | HETERO | LOH |
47 | IV | HETERO | HOMO | LOH |
48 | IV | MSI | HETERO | HETERO |
49 | IV | LOH | LOH | HETERO |
50 | IV | HETERO | HETERO | HETERO |
51 | IV | MSI | HETERO | LOH |
52 | IV | HETERO | HETERO | LOH |
53 | IV | HETERO | HOMO | MSI |
54 | IV | HETERO | HETERO | HETERO |
55 | IV | MSI | MSI | LOH |
56 | IV | MSI | HOMO | LOH |
57 | IV | MSI | HOMO | HETERO |
58 | IV | MSI | HETERO | LOH |
59 | IV | LOH&MSI | HETERO | HETERO |
60 | IV | MSI | MSI | LOH |
61 | IV | HETERO | HETERO | HOMO |
62 | IV | HETERO | HETERO | MSI |
63 | IV | LOH&MSI | LOH | HETERO |
64 | IV | HETERO | LOH | HETERO |
65 | IV | MSI | HETERO | HETERO |
66 | IV | HETERO | HETERO | MSI |
67 | IV | HETERO | HOMO | LOH |
68 | IV | HETERO | LOH | HETERO |
69 | IV | MSI | MSI | MSI |
70 | IV | HETERO | HOMO | HETERO |
71 | IV | LOH&MSI | LOH | HETERO |
72 | IV | HETERO | HETERO | HETERO |
73 | IV | HETERO | HETERO | HOMO |
HETERO, heterozygous; HOMO, homozygous; MSI, microsatellite instability; LOH, loss of heterozygosity.
MSI found by both markers.