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. 2018 Dec 13;14(12):e1007845. doi: 10.1371/journal.pgen.1007845

Table 2. Phenotypic similarities between nup88-/- zebrafish and FADS fetuses.

Danio rerio FADS fetuses Comments
Impaired locomotor behaviour Progressive akinesia
Decreased head and eye size Microcephaly Not in all FADS cases examined
Flat head without protruding mouth Flat face
Lack of pharyngeal arches, dysmorphic jaw Micrognathia
Curvature of the anterior-posterior axis Multiple joint contractures, deformed limbs
Aplastic swim bladder Pulmonary hypoplasia