Table 2.
The inhibitory effect of natural compounds on RANKL‐induced osteoclastogenesis
| Compounds name | Origins | Inhibitory effect on RANKL‐induced osteoclastogenesis |
|---|---|---|
| Madecassoside | Natural | IC50 ≈ 5 μmol L−1 |
| Shikonin | Natural | Toxic |
| Gentiopicroside | Natural | IC50 > 10 μmol L−1 or no effect |
| Stachydrine hydrochloride | Natural | IC50 > 10 μmol L−1 or no effect |
| Calceolarioside B | Natural | IC50 > 10 μmol L−1 or no effect |
| Dicoumarol | Natural | IC50 > 10 μmol L−1 or no effect |
| Alantolactone | Natural | IC50 > 10 μmol L−1 or no effect |
IC50, half maximal inhibitory concentration.