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. 2018 Dec 10;129(1):349–363. doi: 10.1172/JCI123391

Figure 6. Anti-CTLA4 DVD preserves antitumor activity.

Figure 6

(A) C57BL/6j male mice were implanted with TRAMP-C2 tumors at day 0 (D0), and tumors were allowed to grow for 40 days. Mice were randomized into different treatment groups before Ab injection and then received different treatments at days 40, 43, 46, and 49. (B and C) Tumor growth from different treatment groups over time. (D) Survival curve of different treatment groups. Data were conducted with 2 independent experiments. Each treatment arm was collected from 7 mice per group. Bars represent mean ± SEM. *P < 0.05; **P < 0.01; ****P < 0.0001, 2-way ANOVA with post hoc Tukey’s test.