Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Metabolic Stability of SEN001, SEN019, and SEN032 in Human Liver Microsomes
| Compound | Half-Life (min) | CLint (mL/min) | CLH (mL/min) | EH |
|---|---|---|---|---|
| SEN001 | 54.4 | 1491.7 | 747.9 | 0.50 |
| SEN019 | 22.0 | 3692.1 | 1066.7 | 0.71 |
| SEN032 | 3.3 | 24,886.7 | 1414.7 | 0.94 |
CLint, intrinsic clearance; ClH, hepatic clearance; EH, hepatic extraction ratio.
