Figure 2.

Hemostasis and thrombosis are reduced in Tln1^3mutmice. (A) Tail-bleeding time of WT and Tln1^3mut mice (cutoff at 15 minutes; n = 9). (B-C) Onset of thrombus formation (B) and vessel occlusion (C) measured in cremaster muscle venules of WT and Tln1^3mut mice after induction of phototoxic injury (n = 5). (D-E) Thrombus onset (D) and occlusion time (E) in injured cremaster muscle arterioles of WT and Tln1^3mut mice (n = 4). (F) Representative images of WT and Tln1^3mut cremaster muscle venules showing the progress of thrombus formation after 1, 3, 5, and 7 minutes. Scale bar, 25 µm. Values are given as means ± standard errors of the mean; n represents the number of mice. *P < .05.