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. 2018 Oct 4;18:79–87. doi: 10.1016/j.molmet.2018.09.010

Figure 2.

Figure 2

Effects of PVN-MRAP2 overexpression in MC4R expressing neurons on body temperature and brown adipose tissue of female mice. (A) Graph showing body temperature in Mc4r-crePVN-GFP female mice (n = 7) and Mc4r-crePVN-MRAP2 female mice (n = 7) three months after PVN viral injections. (B and C) Graphs showing Real-Time RT PCR data for Ucp1 (B) and Dio2 (C) in brown adipose tissue of female Mc4r-crePVN-GFP (n = 7) and Mc4r-crePVN-MRAP2 mice (n = 7) three months after PVN viral injections. All data are presented as mean ± SEM. *P < 0.05; **P < 0.01 compared to Mc4r-crePVN-GFP mice.