Figure 6.

Summary and integration of pathways affected in liver of fetuses from OB-WSD mothers and corrected with maternal diet reversal in fetuses from OB-DR mothers. Metabolites that increased (solid orange) or decreased (solid blue) in the liver of fetuses from OB-WSD mothers (P < 0.15 in CON vs OB-WSD) are indicated. Metabolites are linked in pathways with a shaded box and dashed outline with indicating overlap when pathways have metabolites in common. Directional arrows are generalized and simplified for illustrative purposes. Metabolites that improved with maternal diet reversal in fetuses from OB-DR mothers are indicated with a green star. Metabolites that had numeric increase or decrease (P > 0.15) are indicated with orange or blue outline (no fill). Metabolites measured but not different have yellow outline. Metabolites that were not measured have no outline. TCA, tricarboxylic acid.