Table 5.
Association between the haplotypes and the risk of lung cancer
| Groups | Frequency[Link] | Group | OR (95% CI) | P [Link] | |
|---|---|---|---|---|---|
| Cases (n) | Controls (n) | ||||
| ERCC1 rs3212986 C>A; ERCC1 rs735482 A>C; ERCC1 rs2336219 G>A | |||||
| CAG | 0.283 | 162 | 177 | 1.000 | |
| CCA | 0.435 | 258 | 264 | 1.068 (0.812, 1.404） | 0.639 |
| AAG | 0.254 | 168 | 136 | 1.350 (0.989, 1.841） | 0.058 |
| CCG | 0.015 | 3 | 15 | 0.219 (0.062, 0.769） | 0.010 |
| ERCC1 rs3212986 C>A; ERCC1 rs735482 A>C; ERCC1 rs2336219 G>A; CD3EAP rs1007616 C>T | |||||
| CAGC | 0.081 | 7 | 90 | 1.000 | |
| CCAC | 0.402 | 254 | 228 | 14.323 (6.503‐31.547) | <0.05 |
| AAGC | 0.232 | 161 | 117 | 17.692 (7.909‐39.576) | <0.05 |
| CAGT | 0.202 | 155 | 88 | 22.646 (10.051‐51.026) | <0.05 |
| CCAT | 0.033 | 4 | 35 | 1.469 (0.405‐5.333) | 0.810 |
| AAGT | 0.021 | 7 | 18 | 5.000 (1.562, 16.005) | <0.05 |
| CCGC | 0.013 | 3 | 12 | 3.214 (0.731, 14.128) | 0.259 |
P‐value <0.05 was considered statistically significant (in bold).
A frequency of <0.01 is not included in the Table.
The P value was obtained using the chi‐square test.