Figure 3.

Fas-deficient BMDCs promote Th2 responses upon HDM treatment. Mice were treated as Figure 1A described. (A) mRNA expression of Il4, Il5, Il13, Ifng, and Il17 in lung tissues was detected by qPCR and normalized to Hprt. (B) Flow cytometry (left), percentage (middle), and cell number (right) of CD4⁺ T cells in lung tissues. (C) Flow cytometry (left) and percentage of IL-4⁺, IL-5⁺, and IL-13⁺ CD4⁺ T cells in lung tissues. (D) Cell number of IL-4⁺, IL-5⁺, and IL-13⁺CD4⁺ T cells in lung tissues. ^*P < 0.05, ^**P < 0.01, ns, not significant. Data are representative of two independent experiments with 4–5 mice (A–D) per group. Student's t-tests (A–D) were performed and data were presented as mean ± SEM.