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. 2018 Dec 21;9:3174. doi: 10.3389/fmicb.2018.03174

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Copyright © 2018 Gan, Yang, Hu, Chen, Zhou, Li, Xu, Wang, Chen and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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p38 regulated poly I:C-induced NETs and ALI. (A) neutrophil elastase (NE) activity was evaluated in the BALF, ^∗p < 0.05; (B) flow cytometry analysis of the BALF cells, ^∗p < 0.05 and ^#p > 0.05; (C) NETs were observed and quantified in lung tissues from mice administered poly I:C and a p38 inhibitor. (D) Claudin-5 and p38 were measured in lung tissues via Western-blot; ^∗p < 0.05.