Table 3.
Serum miRNA results in MD-carriers vs. controls.
| miRNA | MD-carrier | Female controls | p-value |
|---|---|---|---|
| serum levels∗ (×103) | N = 29 | N = 24 | |
| -206 | 38.73 (10.86–70.06) | 0.38 (0.13–0.87) | <0.0001 |
| -144 | 0.00 (0.00–0.00) | 12.65 (9.12–21.03) | <0.0001 |
| -146b-5p | 0.00 (0.00–95.45) | 19.88 (6.41–42.27) | 0.35 |
| -15b | 0.00 (0.00–13.13) | 2.75 (1.24–8.49) | 0.21 |
| -195 | 9.99 (0.58–20.91) | 13.46 (11.74–15.91) | 0.20 |
| -20b | 35.91 (11.55–66.22) | 41.51 (31.65–66.94) | 0.22 |
| -21-5p | 2.92 (0.00–77.28) | 10.55 (7.06–25.90) | 0.40 |
| -221 | 0.00 (0.00–32.99) | 13.59 (0.89–35.06) | 0.06 |
| -222 | 3972.80 (1489.47–6881.28) | 95.65 (67.93–149.18) | <0.0001 |
| -26a | 191.59 (40.72–474.63) | 52.50 (17.12–136.09) | 0.029 |
| -29a | 0.00 (0.00–0.00) | 0.93 (0.00–2.01) | 0.002 |
| -29c | 0.09 (0.00–1.64) | 0.83 (0.00–2.32) | 0.42 |
| -342 | 2633.27 (1194.51–4321.52) | 98.71 (66.63–142.78) | <0.0001 |
| -378a-3p | 3.59 (0.00–88.53) | 0.00 (0.00–0.34) | 0.013 |
| -378a-5p | 53.57 (18.76–170.52) | 0.85 (0.48–1.55) | <0.0001 |
| -451 | 144.0 (0.00–244.83) | 124.83 (103.12–185.29) | 0.68 |
| -93 | 13.50 (0.00–55.57) | 38.71 (27.66–46.52) | 0.11 |
∗Each miRNA serum level was normalized to miRNA-16 serum levels and thereafter multiplied by 103 in order to increase readability. Bold values indicate significant p < 0.05.