Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 27;8:18081. doi: 10.1038/s41598-018-36681-w

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

GR and MR are necessary to mediate stress-related behaviour: (A) Behavioural profiles of 96 hpf zebrafish larvae that were either wildtype [WT], wildtype treated with cortisol [WT + F], GR knockout [GR(−/−)], MR knockout [MR(−/−)] or MR knockout treated with cortisol [MR(−/−) + F]. Mean activity in light and dark is represented, where the activity of 96 hpf larvae is expressed as total distance moved during each 30 s recording bin. The total recording period was 1 h with alternating light periods of 7.5 min each. (B) Total combined distance moved (mm) in the light and (C) total combined distance moved in the dark period. Representative tracking data is included under each bar. Bars represent mean ± SEM (n = 24). Different letters indicate significant differences (One-way ANOVA, p < 0.05). (D) Thigmotaxis: Arenas (wells) were divided into inner and outer zones, and the propensity of 96 hpf larvae to stay close to the outer arena wall was expressed as % of total distance travelled (inner and outer arena) in 30 min. Bars represent mean ± SEM (n = 12). Different letters indicate significant differences. Representative paths for thigmotaxis are shown below each bar.