Table 2.
Associations Between VTA and Raw Change in TRS Score for the 40 Patients with Essential Tremor.
| Unadjusted Analysisa |
Adjusted Analysisa, b |
|||
|---|---|---|---|---|
| Brain Segment (Increase in VTA) | Regression Coefficient (95% CI) | P Value | Regression Coefficient (95% CI) | P Value |
| Prefrontal cortex (50 mm3) | −0.89 (−1.84 to 0.06) | 0.064 | −0.57 (−1.72 to 0.58) | 0.32 |
| Primary motor cortex (50 mm3) | 1.93 (−0.18 to 4.04) | 0.072 | 1.48 (−0.76 to 3.71) | 0.19 |
| Supplementary motor area/premotor cortex (50 mm3) | 1.58 (0.75 to 2.41) | 0.001 | 1.76 (0.76 to 2.76) | 0.001 |
| Total VTA (100 mm3) | 0.12 (−1.19 to 1.42) | 0.86 | 0.09 (−1.20 to 1.38) | 0.89 |
Abbreviations: DBS, deep brain stimulation; TRS, Tremor Rating Scale; VTA, volume of tissue activated.
a
Regression coefficients, 95% CIs, and P values were determined using linear regression models. The regression coefficient indicates the change in the mean raw change in TRS score (preoperative score minus the 6-month follow-up score) that corresponds to the increase in VTA shown in parentheses for each brain segment.
b
Adjusted for age at deep brain stimulation, sex, disease duration, and side of DBS.