Table 1.
Baseline characteristics of pooled cohort across quartiles of soluble ST2 (sST2)
| Participant characteristics | Overall, N (%) | sST2 quartiles (ng/ml), N (%) |
|||
|---|---|---|---|---|---|
| <20.52 | 20.52−26.00 | 26.01−34.14 | >34.14 | ||
| n | 841 | 211 | 210 | 210 | 210 |
| Cohort | |||||
| SKS | 280 | 30 (14) | 52 (25) | 79 (38) | 119 (57) |
| C-PROBE | 561 | 181 (86) | 158 (75) | 131 (62) | 91 (43) |
| Age, yr | 57 (16) | 57 (16) | 56 (16) | 57 (15) | 59 (15) |
| Male | 465 (55) | 78 (37) | 111 (53) | 131 (62) | 145 (69) |
| Race | |||||
| White | 464 (55) | 102 (49) | 123 (59) | 114 (54) | 125 (60) |
| Black | 289 (34) | 86 (41) | 72 (34) | 67 (32) | 64 (31) |
| Other | 86 (10) | 22 (11) | 15 (7) | 29 (14) | 20 (10) |
| Education | |||||
| <High school | 83 (10) | 22 (11) | 14 (7) | 29 (14) | 18 (9) |
| Completed high school | 444 (55) | 105 (51) | 116 (58) | 111 (54) | 112 (57) |
| Completed college or more | 285 (35) | 81 (39) | 69 (35) | 67 (32) | 68 (34) |
| Current smoker | 106 (13) | 25 (12) | 29 (14) | 26 (12) | 26 (12) |
| Prevalent CVD | 303 (36) | 60 (28) | 75 (36) | 76 (36) | 92 (44) |
| Prevalent heart failure | 118 (14) | 14 (7) | 32 (15) | 29 (14) | 43 (21) |
| Statin use | 353 (42) | 74 (35) | 73 (35) | 101 (48) | 105 (50) |
| Diabetes | 354 (42) | 66 (31) | 86 (41) | 88 (42) | 114 (54) |
| Hypertension | 724 (86) | 168 (80) | 182 (87) | 179 (85) | 195 (93) |
| Antihypertensive use | 686 (82) | 161 (76) | 172 (82) | 170 (81) | 183 (88) |
| SBP, mm Hg | 132 (20) | 128 (17) | 134 (22) | 132 (19) | 135 (20) |
| DBP, mm Hg | 75 (12) | 74 (11) | 75 (12) | 74 (12) | 75 (12) |
| BMI, kg/m2 | 31.7 (7.9) | 32.0 (8.3) | 31.0 (6.9) | 32.4 (8.3) | 31.4 (8.0) |
| eGFR, ml/min per 1.73 m2 | 51 (27) | 54 (29) | 51 (27) | 51 (28) | 46 (26) |
| UACR, mg/g | 141 [15−736] | 47 [8−396] | 110 [11−668] | 172 [17−754] | 290 [34−1186] |
BMI, body mass index; C-PROBE, Clinical Phenotyping and Resource Biobank; CVD, cardiovascular disease; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure; SKS, Seattle Kidney Study; UACR, urine albumin-to-creatinine ratio.
Data are N (%) or [interquartile range].