Table 2.
Histological parameters of the cohort
| Variable | High-dose prednisone n = 39 |
First-line CNI n = 11 |
Rescue CNI n = 16 |
P value |
|---|---|---|---|---|
| Columbia classification | 0.233 | |||
| NOS | 18 (45.2) | 4 (36.4) | 4 (25.0) | 0.360 |
| Tip | 6 (15.4) | 2 (18.2) | 5 (31.3) | 0.422 |
| Perihiliar | 11 (28.2) | 4 (36.4) | 3 (18.8) | 0.635 |
| Cellular | 4 (25.6) | 1 (9.1) | 4 (25.0) | 0.367 |
| Global sclerosis (%) | 10 (0–22) | 14 (0–33) | 3 (0–16) | 0.358 |
| Segmental sclerosis (%) | 17 (4–30) | 14 (7–27) | 13 (7–28) | 0.898 |
| Interstitial fibrosis (%) | 20 (10–40) | 10 (10–50) | 13 (10–38) | 0.741 |
| Tubular atrophy (%) | 20 (10–40) | 10 (5–50) | 13 (6–38) | 0.749 |
| Vascular subintimal fibrosis | 17 (43.6) | 3 (27.3) | 6 (37.5) | 0.610 |
| Vascular medial hyperplasia | 12 (30.8) | 2 (18.2) | 5 (31.3) | 0.696 |
CNI, calcineurin inhibitor; NOS, not otherwise specified variant.